Blood Tests for Alzheimer’s

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When it comes to Alzheimer’s disease, early and accurate diagnosis can make all the difference. Until recently, getting that diagnosis often meant invasive procedures like spinal taps or costly PET scans. But new blood tests are changing the game – offering a simpler, more accessible option that could lead to quicker answers and better care.

What’s New in the U.S.?

The U.S. Food and Drug Administration (FDA) recently approved a new blood test called the Lumipulse G pTau217/ß-Amyloid 1-42 Plasma Ratio. While that name is a mouthful, the concept is simple: this test measures two key proteins in the blood that are linked to Alzheimer’s disease. It’s far less invasive than a spinal tap and easier to access than a PET scan.

In clinical studies, this test showed over 90% accuracy when compared with more invasive diagnostic methods. That’s encouraging news for anyone who’s concerned about memory loss or caring for someone who is.

Sweden’s Innovative Approach

Across the ocean, researchers in Sweden are also making strides. A team at Lund University developed the PrecivityAD2 blood test, which works in a similar way – measuring tau and amyloid-beta proteins to detect Alzheimer’s.

In a large study of 1,200 adults (average age: 74), the Swedish test identified Alzheimer’s pathology with about 90% accuracy. Importantly, it worked well in both memory clinics and regular doctor’s offices – settings where older adults are most likely to start raising concerns.

Why This Matters

Here’s a quick comparison of the two tests:

Test Name	Country	What It Measures	Accuracy	Invasiveness
Lumipulse	U.S.	Tau & amyloid-beta proteins	~91–97%	Blood draw
PrecivityAD2	Sweden	Tau & amyloid-beta proteins	~90%	Blood draw

Both tests are done with a simple blood draw – a major improvement in comfort and convenience.

Even more importantly, they offer a way for doctors – especially in primary care – to identify Alzheimer’s earlier and more accurately. This could reduce stress and uncertainty for families while opening doors to treatment and planning.

A Word of Caution

While these tests are exciting, they’re just one piece of the puzzle. Experts remind us that a diagnosis should always include a full clinical evaluation. Blood tests can tell us a lot, but they can’t replace the insight of a healthcare professional who understands the full picture – medical history, lifestyle, and personal concerns.

As Dr. Verna Porter puts it, “Early and accurate diagnosis can lead to timely intervention and better patient outcomes.” But, as Dr. Karen D. Sullivan adds, we need to be careful not to rely solely on lab results – individualized care remains key.

Looking Ahead

These new blood tests are helping us move toward a future where diagnosing Alzheimer’s is faster, easier, and more accessible. That’s good news for older adults, caregivers and healthcare providers alike.

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